Please visit the Scimone Lab's webpage: (Link above)
Dr. Scimone is an assistant professor in Biotechnology at UNH Manchester. He teaches courses in the areas of cell culture, microscopy, and neuroscience. His research lab is focused on new experimental techniques in cellular neuroscience, optics, and image analysis, where he mentors both undergraduate and graduate students.
Courses Taught
- BIOT 753/853: Cell Culture
- BIOT 780/880: Techn Microscop Image Analysis
- BIOT 853: Cell Culture Lab
- BIOT 893: Directed Graduate Research
- BIOT/BSCI 897/797: SpcTop/Neurobiotechnology
Research Interests
- Neuroscience
- Traumatic Brain/Head Injury
- Cytoskeleton
- Microscopy
- Optics
- Image Processing
Selected Publications
Asquith, N. L., Becker, I. C., Scimone, M. T., Boccia, T., Camacho, V., Barrachina, M. N., . . . Italiano, J. E. (2024). Targeting cargo to an unconventional secretory system within megakaryocytes allows the release of transgenic proteins from platelets.. J Thromb Haemost, 22(11), 3235-3248. doi:10.1016/j.jtha.2024.07.021
Yu, T. C., Davis, S. J., Scimone, M. T., Grimble, J., Maguluri, G., Anand, S., . . . Zhao, Y. (2023). High Sensitivity Singlet Oxygen Luminescence Sensor Using Computational Spectroscopy and Solid-State Detector.. Diagnostics (Basel), 13(22). doi:10.3390/diagnostics13223431
Scimone, M. T., Krishnamurthy, S., Maguluri, G., Preda, D., Park, J., Grimble, J., . . . Iftimia, N. (2021). Assessment of breast cancer surgical margins with multimodal optical microscopy: A feasibility clinical study.. PLoS One, 16(2), e0245334. doi:10.1371/journal.pone.0245334
Estrada, J. B., Cramer, H. C., Scimone, M. T., Buyukozturk, S., & Franck, C. (2021). Neural cell injury pathology due to high-rate mechanical loading. Brain Multiphysics, 2, 100034. doi:10.1016/j.brain.2021.100034
Scimone, M. T., Cramer, H. C., Hopkins, P., Estrada, J. B., & Franck, C. (2020). Application of mild hypothermia successfully mitigates neural injury in a 3D in-vitro model of traumatic brain injury.. PLoS One, 15(4), e0229520. doi:10.1371/journal.pone.0229520
Scimone, M. T., Cramer Iii, H. C., Bar-Kochba, E., Amezcua, R., Estrada, J. B., & Franck, C. (2018). Modular approach for resolving and mapping complex neural and other cellular structures and their associated deformation fields in three dimensions.. Nat Protoc, 13(12), 3042-3064. doi:10.1038/s41596-018-0077-7
Bar-Kochba, E., Scimone, M. T., Estrada, J. B., & Franck, C. (2016). Strain and rate-dependent neuronal injury in a 3D in vitro compression model of traumatic brain injury.. Sci Rep, 6, 30550. doi:10.1038/srep30550
Estrada, J. B., Scimone, M. T., Landauer, A. K., & Franck, C. (2016). Microcavitation as a Neuronal Damage Mechanism in Blast Traumatic Brain Injury. Biophysical Journal, 110(3), 320a. doi:10.1016/j.bpj.2015.11.1717